Definiens Webinar Series
We would like to invite you to join our webinar series. Our online presentations and workshops are about image analysis breakthroughs from industry leaders and Definiens. Registration is required for these events.
Upcoming Webinars
Webinar: Introducing Definiens Tissue Studio 3.0
Recordings available
Please click here to see the webinar recordings on uTube
Join this webinar to learn more on Definiens Tissue Studio® 3, the new version of the leading Image Analysis Solution for Quantitative Digital Pathology. It combines highly detailed quantification of a tissue specimen with a straightforward and fast out-of-the-box configuration workflow. Get an overview about Definiens Tissue Studio® 3 and its new features. These include:
- New improved Region-of-Interest Detection
- Quantification of Nucleus Morphology
- a new Angiogenesis Module
Date: Wednesday, November 9
Time: 5 pm CET / 11am EST / 8am PST
Featured Speaker(s)
Dr. Florian Leiss (Trainer and Marketing Specialist)Dr. Christian Sendner (Application Engineer Life Sciences)
Webinar: Definiens presents a new Generation of Products for Quantitative Digital Pathology and Biomarker Research
Recordings available
Please click here to see the webinar recordings on uTube
Are you interested in Quantitative Digital Pathology and Biomarker Research?
Discover Definiens' new generation of products for image analysis and integrated data mining. A significant step on the way to turning pathology into a quantitative discipline.
Definiens Tissue Studio® 3 is the new version of the leading Image Analysis Solution for Quantitative Digital Pathology. It combines highly detailed quantification of a tissue specimen with a straightforward and fast out-of-the-box configuration workflow. New features include an improved detection of regions-of-interest, classification of nuclear morphology and an angiogenesis module.
Definiens Developer XD 2 is the most powerful development environment for automated image analysis that addresses a wide scope of functions in biomedical image analysis with unprecedented depth and accuracy. This updated version addresses a series of requirements suggested by the user community including very large data processing and machine learning functionality.
Definiens Image Miner 1, the novel technology component in this portfolio of products, closely integrates data mining with image analysis to accelerate biomarker research. It profiles tissue probes for clinically or diagnostically relevant differences in morphology or biomarker expression. Development and quality control are supported by seamless links between data points and the visual inspections of associated regions in the tissue.
Date: Wednesday, October 26
Time: 5 pm CET / 11am EST / 8am PST
Featured Speaker(s)
Dr. Martin Baatz (VP Marketing)Arno Schäpe (Chief Architect)
Past Webinars
Free Webinar: An Integrated Digital Pathology Workflow for Digital Slide Scanning, Image Management, and Image Analysis
Aperio and Definiens are proud to present:
An Integrated Digital Pathology Workflow for Digital Slide Scanning, Image Management, and Image Analysis
In this complimentary one hour webinar, you will learn about the new solutions available as a result of the partnership between Aperio and Definiens.
Topics include:
- Integrating image acquisition, management, and analysis workflow
- Aperio’s Spectrum database management software for managing digital slides
- A demo of Definiens’ Tissue Studio for Her2 analysis in breast cancer tissue sections
Date: Wednesday, July 6
Time: 11am EST / 8am PST
Featured Speaker(s)
Aperio: Will Casavan - Product ManagerAperio: Priya Vaidyanathan - Image Analysis Specialist
Definiens: Dr. Florian Leiss - Trainer and Marketing Specialist
Webinar: Clarient PATHSiTE Scope IA: Improving Patient Care - Powered by Definiens.
Please Join Definiens with special guest Dr. Roscoe Atkinson, M.D. from Clarient Inc. for a free webinar:
Clarient PATHSiTE Scope IA: Improving Patient Care - Powered by Definiens.
Topics that will be covered:
- The evolution and development of Image Analysis and Scope IA at Clarient Inc.
- Clarient’s utilization of Definiens algorithms and technology
- How Clarient’s application of Scope IA and Definiens improves patient care
Space is limited.
Please reserve your Webinar seat now at:
https://www2.gotomeeting.com/register/173191610
Featured Speaker(s)
- Dr. Roscoe Atkinson, M.D. - Pathologist, Clarient- Peter Duncan - Director, Marketing and Business Development Translational Research, Definiens
Image Analysis Strategies for Challenging Biomedical Images using Definiens Developer XD™
Learn image analysis strategies from the pros at Definiens using Definiens Developer XD on the following examples:
- The Rolling Ball Method for Correcting Heterogeneous Backgrounds in Fluorescently Stained Golgi Cells
- Three Dimensional Analysis of Dendritic Spines
- Classifying Tumor vs. Non-Tumor and Tumor Morphology in Non-Small Cell Lung Cancer
After registering you will receive a confirmation email containing information about joining the Webinar.
Featured Speaker(s)
Peter Duncan – Director, Marketing and Business DevelopmentDr. Thomas Mrowiec – Consultant, Professional Services
Dr. Florian Leiss – Trainer and Marketing Specialist
What's new with Definiens Tissue Studio 2.1?
New in Definiens Tissue Studio 2.1:
- Fluorescence enhancements:
Support for 10–16 bit data
Visualization of colocalization per cell / per nucleus
Export of Pearsons/Manders correlation coefficient (for cells and nuclei) - Bright field enhancements:
Intensity-based classifications
Option to use optical density instead of IHC marker density
Membrane Classification into three intensity classes
Marker Area Classification into four intensity classes - Breast panel:
Her-2 scoring (DAKO and ASCO) on a cell-by-cell basis
Allred score - Additional context features:
Distance of objects to region border, e.g. ‘Distance of 3+ cells to tumor border’.
Featured Speaker(s)
Dr. Kai Hartmann - Product Manager, DefiniensPeter Duncan - Director, Marketing and Business Development, Translational Research, Definiens
Image Analysis vs. Manual Evaluation of Her2 in Esophageal Cancer
Have you have ever wondered how digital pathology image analysis compares to manual evaluation of Her2 stained tumor biopsies?
Dr. Guenter Schmidt et al. have recently presented their findings in a study comparing manual H-score evaluation (Dako Herceptest) of esophagogastric TMA cores compared to an algorithm derived using Definiens Developer™ software.
Kaplan-Meier Analysis revealed a significant prognostic value for the two groups generated by image analysis results, whereas the visually assessed score was not significant.
Join us for a review of this study and the results; including how H&E morphological evaluation compared to the Her2 Dako Herceptest with respect to patient stratification.
Featured Speaker(s)
Peter Duncan - Director, Marketing and Business Development Translational Research, DefiniensDr. Guenter Schmidt - Director, Product Management, Definiens
Introducing: Definiens Tissue Studio™ 2.0
New in Definiens Tissue Studio™ 2.0:
- Full immunofluorescence support: Nuclear, membrane & cell detection; Cell simulation; Biomarker co-localization; Tissue microarray core detection; Full multiparametric quantification of all objects (cells or sub-cellular compartments); 12-color channel support.
- Improved nucleus detection for bright field images
- Customized "tuning" of Definiens Composer™ technology
- Faster performance
- And - still simple to use!
Featured Speaker(s)
Dr. Kai Hartmann - Product Manager, DefiniensPeter Duncan - Director, Marketing and Business Development, Definiens
Image Analysis as a Tool for Prognostic and Predictive Biomarkers in Breast Cancer - How Reliable Is It?
Topics covered:
- Current standards in IHC and pathology
- Advantages of automated image analysis
- How Definiens Tissue Studio is used for digital pathology image analysis
- Case study comparing Definiens Tissue Studio analysis results with "gold standard" immunohistochemistry Her2 and ER best practices.
- Results
Featured Speaker(s)
Dr. Marilyn Bui - Scientific Director of Analytic Microscopy CoreMoffitt Cancer Center, Tampa, Florida
Mark Lloyd - Staff Scientist in the Analytic Microscopy Core
Moffitt Cancer Center, Tampa, Florida
Peter Duncan - Director, Business Development Clinical Diagnostics
Definiens
SOX2 Evaluation in Non-small Cell Lung Cancer using Definiens Tissue Studio
In this talk, a study on SOX2 amplification in non-small cell lung cancer with a special focus on IHC assessment using the Definiens Tissue Studio image analysis software will be presented.
The aim of the study was to verify SOX2 amplification and protein over-expression in non-small cell lung cancers (NSCLC) and to compare these results with patient and tumor characteristics. A total of 940 NSCLCs from two independent population-based cohorts containing predominantly adenocarcinomas of the lung and squamous cell lung carcinomas, were assessed by fluorescence in-situ hybridization (FISH) and immunohistochemistry (IHC) to study SOX2 amplification and expression level. For protein expression analysis, the expression level was explored by utilizing Definiens Tissue Studio.
This webinar was recorded.
Featured Speaker(s)
Sven Perner: Assistant Professor - Institute of Pathology, Comprehensive Cancer Center, University Hospital TuebingenTheresia Wilbertz: PhD Candidate - Institute of Pathology, Comprehensive Cancer Center, University Hospital Tuebingen
What's New with Definiens Tissue Studio 2.0?
Topics:
- The "Magnetic Snap" feature: Manual Selection of regions of interest with the outlining tool on native image resolution
- Preselection of regions of interest with Definiens Composer Technology
- Nucleus and Cell Qualification
- Easier access of results
- Selecting regions of interest in tissue microarray cores with Definiens Composer Technology
- Bulk import for tissue microarray core metadata
- Tissue Studio for enterprise environments
And finally, a sneak preview of Definiens Tissue Studio 2.0!!
Featured Speaker(s)
Dr. Kai Hartmann, Product ManagerPeter Duncan, Director, Marketing and Business Development
Definiens Image Analysis - An Enabling Platform for Personalized Medicine
"Personalized Medicine" is a concept that has been recognized as a key driver to reduce attrition rates and increase response rates for patients receiving therapeutic treatment. Vital to this effort will be the development and implementation of more accurate diagnostics.
In this talk, we presented how Definiens image analysis is playing, and will continue to play a vital role in getting the right drug, to the right patient, at the right time.
Featured Speaker(s)
Dr. Martin Baatz, Vice President, Solutions and ServicesPeter Duncan, Director, Business Development - Clinical Diagnostics
About Definiens
The Health Image Intelligence Company™
Definiens is a leading Health Image Intelligence™ company that develops software solutions for biomedical image analysis, data mining and clinical decision support. The company’s software analyzes images from cell-based assays, whole tissue slides and full body scans and allows users to correlate this information with data derived from other sources, supporting better decisions in research, diagnostics and therapy.
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