Definiens LymphExpert™

Lymph nodes play a critical role in the assessment of the spread of cancer through the lymphatic system and the staging of almost all types of cancer and therapy control. The earlier the metastatic spread of cancer can be detected, the higher the chances are for successful treatment.

Definiens LymphExpert™ is Definiens first medical imaging application and facilitates the automated volumetric analysis of lymph nodes.

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Definiens LymphExpert™

Definiens LymphExpert™ helps radiologists and other medical experts to detect, analyze and quantify the size of lymph nodes over time. The pioneering software application facilitates the early detection of the metastatic spread of cancer. The software application

assesses lymph nodes accurately according to the RECIST and WHO criteria.
quantifies lymph nodes volumetrically over time which gives the most accurate assessment of their change in size.
provides reproducible and consistent measurements, in a standardized manner, independent of the user.

Definiens LymphExpert™ side-by-side view of prior and current lesion in 2D and 3D:


PRIOR lesion in 2D	CURRENT lesion in 2D	PRIOR lesion in 3D	CURRENT lesion in 3D

Definiens LymphExpert™ speeds up analysis and increases accuracy. It benefits organizations all along the healthcare value chain:

Teleradiology Service Providers

Pharmaceutical Companies

Radiology and Oncology Care Provider

Cancer Centers &
Academic Institutions

Imaging Contract Research
Organizations (CROs)

Benefits of Definiens LymphExpert™

Customer references

The accuracy of Definiens LymphExpert™ was demonstrated in a clinical study conducted by Peter Herzog MD at the University Hospital of Munich / Grosshadern:

"Definiens LymphExpert™ automatically segments, extracts and quantifies lymph nodes that are so small
that the average human reader cannot reliably detect changes in size while also providing the volumetric
measurements that other methods of imaging lack. This allows for increased detection performance re-
garding the number of detected lymph nodes as well as size changes.”

Peter Herzog, MD at the University Hospital of Munich / Grosshadern

Imaging Service AG is a leading provider of teleradiology services in Germany. It provides round-the-clock high-quality diagnoses of CT and MRI images for hospitals that do not have the capability to analyze their images in-house. Imaging Service utilizes Definiens LymphExpert™ to analyze lymph nodes on CT images:

“Imaging Service AG provides hospitals across Germany with rapid radiological services for a number of
diseases. Employing Definiens LymphExpert™ greatly increases our ability to provide efficient, accurate
diagnostic services for cancer patients.”

Barna Almasi, CEO, Imaging Service AG

For further information, please download our NEW product brochure Definiens LymphExpert™ and read what clinical experts say about our innovative medical imaging software (the article was published in Nov 2008 by European Hospital).