Biomarker Expression Profile on a Cell-by-Cell Basis |in a Highly Multiplexed Immunofluorescence (IF) Assay

Multiplexing is the key for generating high-dimensional readouts of a set of biomarkers. New immunofluorescence technologies allow multiplexing of more than 20 proteins per specimen. This example shows how the application has detected tumor cell populations, individual cells, and cellular sub-structure. It facilitates a highly detailed readout of measurements for all markers on a cell-by-cell basis, yielding a very large number of detailed endpoints that can be used as a basis for subsequent correlation studies.

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