Definiens provides a configurable environment for developing, running, and validating image analysis procedures for any type of assay in 2D or 3D, as well as over time. Our image analysis solutions address the entire spectrum of imaging modalities and data formats available today, and they integrate seamlessly with the equipment and workflows typically found in most research facilities. Our software can be used for the analysis of any high content imaging data, providing an unsurpassed level of readout detail and accuracy thanks to the precise segmentation of cells, cell compounds, and other structures of interest.
Here are some examples of how Definiens is being used to address various challenging image analysis tasks:
3D Analysis of Murine Fibroblasts
Morphological Rearrangements
Membrane Trafficking
Measuring the Spatial Relationships of Endosomes in Hepatocytes
Automated Detection of Zebrafish Larvae Tissues
3D Analysis of FISH in Whole Zebrafish Heart
"Definiens software opens new possibilities for our High Content Analysis (HCA) applications, especially when dealing with cell-based 3D datasets, where Definiens outperforms any other HCA dedicated software available."
Nikić I, Merkler D, Sorbara C, Brinkoetter M, Kreutzfeldt M, Bareyre FM, Brück W, Bishop D, Misgeld T, Kerschensteiner M:
A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis
Nature Medicine,
Published online 27 March 2011
Definiens is a leading Health Image Intelligence™ company that develops software solutions for biomedical image analysis, data mining and clinical decision support. The company’s software analyzes images from cell-based assays, whole tissue slides and full body scans and allows users to correlate this information with data derived from other sources, supporting better decisions in research, diagnostics and therapy.
