Image Analysis Applications for Life Sciences

Definiens has over seven years of experience working with customers in Life Sciences. Our unique blend of technology, products and domain knowledge has enabled our customers to solve a vast array of image analysis problems at all stages of the drug development lifecycle. Definiens technology can address images of any type (2, 3 or 4D), from any instrument or source, with any degree of complexity. It creates rapid, automatic and accurate image analysis solutions for all modern imaging instruments, including optical microscopy, digital slide scanners, MicroCT and optical non-invasive scanners. The technology captures the expertise of scientists in its ruleware ensuring an extremely high degree of accuracy and consistency in its interpretation of imagery. Particular areas of expertise in Life Sciences are:

• Cell-based assays
  Automated image analysis is commonly used in high-content analysis. However, the current image analysis products on the market are narrow in scope, platform-dependent, proprietary and perform well only on the simplest of image analysis tasks. Definiens Cellenger® is a truly platform-independent image analysis system designed specifically for high-content assays which also allows cell-based assay data to be combined with data from other systems such as digital slide scanners.
• Histopathology
  Conventional manual screening processes are labor intensive and costly. They run a significant risk of human error in identifying efficacy and toxicity profiles. Compounding the challenge, statutory regulations are becoming increasingly stringent with a demand for more accurate and consistent data. Definiens automated digital pathology solutions deliver accurate and consistent results on even large tissue samples, identifying, for example, areas of interest for an expert to examine in greater detail.

• Non-invasive imaging
  The degree of progression of a malignancy is not easy to determine and an early stage cancer can escape attention because the diagnostic question draws the focus to a different organ. For a long time doctors and scientists were only supported by image alteration techniques that improved the contrast, moved thresholds or introduced threshold color coding. Definiens' technology classifies and analyzes imagery using all semantic information available. It provides an extremely accurate method of determining, for example, the spread of a malignancy or the presence of an early stage cancer.

For additional information on current customers and how they are using Definiens software to solve their image analysis challenges, please visit our customer references and case study pages!

Life Sciences Applications

We offer Life Sciences applications that accelerate the development of image analysis solutions by bringing together the required image analysis rule-sets, workflows, data management and visualization tools in a simple to use and install environment.

Definiens Cellenger for MVA in cell based assays analyzes cell-based and high content assays.	Definiens TissueMap automated digital pathology software for reliable identification of  tissue sections.