Discovery

Definiens can be used for all high-content imaging assays, supporting target identification and lead optimization. Typical assays include 2D cell-based high-content screening, 3D cell imaging, and simple vertebrate models like C.elegans or zebrafish. Definiens offers the ability to measure hundreds of descriptors related to morphology, rare cell events and motility, which greatly assists the prioritization of drug candidates.

Definiens also enables the discovery of new disease-related pathways and biomarkers in tissue-based assays for many different disease areas including oncology, cardiovascular, neurology, and inflammation. 3D small animal imaging studies support the generation of time lapse data points.