Videos

Mar 12, 2012

Definiens Corporate Video

The Definiens 2012 corporate video provides an overview of the advantages of Quantitative Digital Pathology and the benefits from using Definiens leading solutions for image and data analysis. It includes...
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Apr 1, 2015

Working in the Definiens Product Development Team

Watch this video to get an impression on how it's like to work at Definiens, in the product development department. Lean back and enjoy!
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Nov 17, 2014

Tissue Phenomics - A Novel Big Data Approach in Pathology

Data mining techniques and big data approaches have the power to create knowledge that cannot be created otherwise. And while they are well established, only recently have people become aware of the impact these techniques and approaches have on their daily life. The main reason for this is the dramatic...
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Nov 17, 2014

Immunoscore / Immunoprofile: Assessing Anti-Cancer Immunity as a Biomarker to Stratify Patients for Clinical Trials

There is a significant need for innovative prognostic and predictive biomarkers of recurrence, response to therapy, and survival for patients with cancer. Increasing evidence suggests that the number, type and location of tumor-infiltrating lymphocytes in primary tumors has prognostic value, and this has led to the development of an “immunoscore”....
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Nov 17, 2014

Tissue Phenomics: From Biomarker Discovery to Clinical Diagnostic Assay Commercialization

Definiens’ Cognition Network Technology®, CNT, provides detailed tissue biomarker readouts from digital pathology slides, and enables the correlation of this information with clinical outcome and genomic data, an approach known as Tissue Phenomics. The manual approach to analyzing tissue provides mostly limited, qualitative information. However using CNT, thousands of quantitative,...
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Nov 17, 2014

Use of Computer Tumor Tissue Imaging Algorithms to Assess the Role of Microenvironment in Melanoma Brain Metastases

Background: High intratumoral hemorrhage and low degree of immune infiltrates in craniotomy specimens from melanoma brain metastases (MBM) are associated with shorter overall survival (OS). We hypothesize that immune checkpoint proteins (ICP), angiogenic factors, hypoxia, and the density of mature vs. immature blood vessels (MBV, IBV) are important prognostic factors.Conclusions:...
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